PET tracer development

Suggested Reading

The following papers give an excellent overview of the process and considerations when developing new PET tracers:

G.C. Van De Bittner, E.L. Ricq, and J.M. Hooker. A philosophy for CNS Radiotracer Design. Accounts of Chemical Research 47: 3127;-3134, 2014 (Journal link)

Software / online tools

• http://www.swissadme.ch/index.php (SwissADME - tool to compute physicochemistry and estimate the pharmacokinetics, druglikeness and medicinal chemistry friendliness of small molecules)
• http://www.proteinatlas.org/ - tool to compare normal and cancerous protein expression of tissues and cells