Tutorials

During our group meeting time (Tuesdays 9am-11am), we hold tutorial sessions on an occasional basis. These are teaching-style presentations made by group members on various topics related to research projects in our lab. These tutorials are open to all members of the Crump Institute for Molecular Imaging and other attendees will be considered upon request.

Upcoming Tutorials

None currently scheduled

Past Tutorials

2019-02-27

09:00 - 11:00

CNSI 5429

Significant figures and error estimation

Michael van Dam

Outline:

Significant figures
Propagation of significant figures when performing calculations
Measurement uncertainty and relation to significant figures
Uncertainty estimates (standard deviation, etc.)
Propagation of uncertainty when performing calculations
Good practices when presenting data

2019-01-09

09:00 - 11:00

CNSI 5429

Organic chemistry principles

Travis Holloway

Outline:

High-level overview
Part I: Molecular Shape
- Naming (functional groups, chains, branching)
Part II: Bonding
- Polarity
- Electrophiles, nucleophiles, formal charge
- Reactions and arrow pushing
Part III: Reactivity
- Reaction equations
- Equilibrium constant and free energy
- Energy diagrams and transition states
- Methods to reduce free energy
  - Temperature
  - Solvent effect (polarity)

2018-12-19

09:00 - 11:00

CNSI 5429

and

2018-12-05

09:00 - 11:00

CNSI 5429

Introduction to molecular imaging modalities

Ksenia Lisova

Outline:

Overview of optical imaging methods and microscopy techniques
- Bright-field, phase-contrast, coherence tomography, diffuse optical tomography, luminescence microscopy and imaging, fluorescence microscopy, confocal microscopy, electron microscopy, scanning probe microscopy, mass spectrometry imaging, Cerenkov imaging, thermography
- Summary
Overview of magnetic resonance imaging (MRI) techniques
- MRI, Functional MRI, MR angiography, perfusion contrast imaging, diffusion contrast imaging, magnetic resonance spectroscopy, F-19 MRI
- Summary
Overview of ultrasound imaging techniques
- Ultrasound, contrast-enhanced ultrasound, photoacoustic imaging
- Summary
Overview of X-ray imaging techniques
- Projection radiography, dual-energy projection radiography, fluoroscopy (real-time imaging), X-ray computed tomography, contrast-enhanced CT, CT perfusion imaging
- Summary
Overview of radionuclide imaging techniques
- Scintigraphy (2D), SPECT, PET, PET/MRI
- Summary and comparison

2017-06-27

09:00 - 11:00

CNSI 5230

Introduction to fluorine-18 radiochemistry and radiochemistry nomenclature

Ksenia Lisova

Outline:

Challenges and general approaches in 18F-radiochemistry
Overview of different labeling methods
- Nucleophilic fluorination
- Electrophilic fluorination
- Strategies for labeling biological molecules
Introduction to radiochemistry nomenclature, including recent recommendations from SRS

2017-05-02

09:00 - 11:00

CNSI 5230

Introduction to LabVIEW

Jason Jones

Outline:

Basic principles and architecture of LabVIEW
Program flow structures ("for" loops, "while" loops, sequences, case structures, state machines)
Data structures (arrays, ...)
Linking to DAQ with myDAQ

2017-04-18

09:00 - 11:00

CNSI 5230

Introduction to photolithography and PDMS chip fabrication

Noel S. Ha

Outline:

Principles of photolithography
Mask design considerations (positive/negative resist, PDMS shrinkage)
Preparation of master molds
Preparing, molding, bonding, punching PDMS chips
Using PDMS as a mold material (why?, silanization)
Tips and tricks

2015-10-21

10:00 - 11:00

CNSI 5230

Introduction to HPLC

Shilin Cheung

Outline:

HPLC operation
Scale (analytical vs semi-preparative)
Column types (reversed / normal phase)
Radio-HPLC
Understanding chromatograms
Injection and cleaning procedure

2009-05-13

Introduction to pneumatic and fluidic fittings

R. Michael van Dam

Outline:

Elements of pneumatic and fluidic systems
- Tubing and manifolds
- Connectors
  - Types (barbed, compression, one-touch / quick-connect), material, sex
  - Categories (unions, elbows, adapters, Ys / Ts, plus, caps, N-way unions)
Fluidic connections
- Fluidic tubing (materials, sizes, tubing sleeves)
- Common fittings (1/4-28 flat, 10-32 coned, 6-32 coned, 6-40 flat, Luer-Lok, Omni-Fit)
- Common adapters
Pneumatic connections
- Pneumatic tubing (materials, sizes, limitations)
- Common fittings (one-touch, NPT sizes, other sizes: 10-32, M3, M5, barbed, Swage-Lok, solder joints)
- Common adapters
Conclusions and final consdierations

2009-04-13

F-18 radiochemistry: terminology for yields and purities

R. Michael van Dam

Outline:

Introduction to common analytical methods
- Radio-TLC
- Radio-HPLC
Specify carefully what yield / efficiency you mean (start point, end point)
Radiochemical purity versus yield

2008-07-02

Introduction to SolidWorks

R. Michael van Dam

Outline:

What is Solidworks?
Online learning resources
Overall design strategy: 2D sketches converted to 3D
Constraint-driven design
2D sketch primitives (lines, rectangle, circles, arcs, construction lines)
3D conversion (extrude, cut, revolve around axis, hole wizard)
Additional tools (chamfers, fillets, arrays/grids, mirror, reference geometry)
There are many ways to draw any part -- choose a way that will make anticipated changes easy
Machinability
- Common machining operations after sawing (facing, milling, pocketing, drilling, tapping, reaming)
- Limitations (e.g. inside pockets generally cannot have perfectly square edges; holes can't bend internally)
Demonstration/exercise

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